YAY for Sleep!

[Anonymous]

I do not know either…I have not heard of Prevacid Powder before. Hopefully the doc or the pharmacist can give you instructions.

[Anonymous]

Maybe ask for another form of Prevacid. The solutabs are very easy to give, but they do contain lactose so they may bother Quinn’s tummy if she’s lactose intolerant. Also there are Prevacid capsules that you break open and pour over applesauce.

[Anonymous]

Ok. Here is what Ive found so far. Maybe we can both do some research and come up with an answer because I have tried to word my search many ways and I cant seem to find at what amount does sdium bicarbonate become toxic in infants.

Here is what I have found so far

http://www.rxlist.com/cgi/generic/zegerid.htm

ZEGERIDÃ? (omeprazole/sodium bicarbonate) is a combination of omeprazole, a proton-pump inhibitor, and sodium bicarbonate, an antacid. Omeprazole is a substituted benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, a racemic mixture of two enantiomers that inhibits gastric acid secretion. Its empirical formula is C₁₇H₁₉N₃O₃S, with a molecular weight of 345.42. The structural formula is:

Omeprazole is a white to off-white crystalline powder which melts with decomposition at about 155° C. It is a weak base, freely soluble in ethanol and methanol, and slightly soluble in acetone and isopropanol and very slightly soluble in water. The stability of omeprazole is a function of pH; it is rapidly degraded in acid media, but has acceptable stability under alkaline conditions.

ZEGERID is supplied as immediate-release capsules and unit-dose packets as powder for oral suspension. Each capsule contains either 40 mg or 20 mg of omeprazole and 1100 mg of sodium bicarbonate with the following excipients: croscarmellose sodium and magnesium stearate. Packets of powder for oral suspension contain either 40 mg or 20 mg of omeprazole and 1680 mg of sodium bicarbonate with the following excipients: xylitol, sucrose, sucralose, xanthan gum, and flavorings.

http://www.rxlist.com/cgi/generic/sodbic_ids.htm

In infants (up to two years of age), the 4.2% solution is recommended for intravenous administration at a dose not to exceed 8 mEq/ kg/ day. Slow administration rates and the 4.2% solution are recommended in neonates, to guard against the possibility of producing hypernatremia, decreasing cerebrospinal fluid pressure and inducing intracranial hemorrhage.

http://www.viha.ca/NR/rdonlyres/46C36BE4-C6DD-4B42-B4BB-67C7 5F66FC62/7201/sodium_bicarbonate2.pdf

PAEDIATRIC

• Infants 5 kg or less: 4.2% (0.5 mmol/mL) or more dilute solution.3

• Maximum dose in children 2 years or less: 8 mmol/kg/24 hours.1

[Anonymous]

This is all I could find and this study is in newborns:

The effects of sodium bicarbonate on brain blood flow, brain water content, and blood-brain barrier in the neonatal dog Journal Acta Neuropathologica Publisher Springer Berlin / Heidelberg ISSN 0001-6322 (Print) 1432-0533 (Online) Issue Volume 65, Number 2 / June, 1984 Category Original Works DOI 10.1007/BF00690465 Pages 124-127 Subject Collection Medicine SpringerLink Date Sunday, December 12, 2004 Add to marked items Add to shopping cart Add to saved items Request Permissions Recommend this article Original Works The effects of sodium bicarbonate on brain blood flow, brain water content, and blood-brain barrier in the neonatal dog R. S. K. Young1 , S. K. Yagel1 and C. L. Woods1 (1) Dept. of Pediatrics, Division of Neurology, The Milton S. Hershey Medical Center, The Pennsylvania State University, P.O. Box 850, 17033 Hershey, PA, USA Received: 15 March 1984 Accepted: 18 July 1984 Summary To explore the relationship between cerebral hemorrhage in the newborn and administration of sodium bicarbonate, we gave a standard dose of sodium bicarbonate (5 mEq/kg) to neonatal dogs and then assessed changes in cerebral blood flow, brain water content, and the blood-brain barrier. This dose of sodium bicarbonate produced no increase in blood pressure or cerebral blood flow and no alteration in blood-brain barrier. However, infusion of sodium bicarbonate did cause hyperosmolality and hypernatremia and a significant decrease in brain water content. Cerebral hemorrhage in the neonate associated with infusions of sodium bicarbonate may be related to shifts in brain water rather than to changes in blood pressure or cerebral blood flow. Key words Sodium bicarbonate – Blood-brain barrier – Cerebral blood flow – Hyperosmolality Supported in part by NIH grant NS 18039 (RSKY)

[Anonymous]

The salt dries up the body and thats basically what Sodium Bicarbonate is. So if the body has too much salt, it can cause brain damage.

I guess what we need is to know how much salt (sodium bicarbonate) is too much salt for children 2 and under.

[Anonymous]

Also we have tried all the other forms of prevacid but the powder and every other PPI on the market.

Dosing is 1/4 a packet of powder twice a day with 1 1/2 ml of mylanta

[Anonymous]

I made a topic in Medicine

[Author]

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