Is anyone taking more than 10 mg/kg/day of Zantac?

[Anonymous]

My son is 8 1/2 months, 19lbs and is taking 16 mg/kg/day, which comes out to 3mls 3 times a day. He seemed to be doing better on this dosage until the crazy peak around 7 months. Since he should be almost done with reflux, I didn’t want to change to a new med this late in the game.

Has anyone else had experience with this high of a dosage. If so, did you see anything negative come from it?

[Anonymous]

DS is on a different med. so I cna’t offer alot of help. He takes Prilosec in a compounded suspension form. We get it done at a RELLY good pharamacy in our hcildren’s hospital. He has been on as hig as 5cc twice per day of 20mg over 5ml of the suspension mix.

[hellbennt]

sheri should see this post soon

[Anonymous]

DH is a pharmacist and just looked it up in his palm pilot and it said that the max dose in a 24hr period is 300mg and from what you are saying it sounds like he is getting 45mg x3/day which would be 135mg. So it sounds like you are fine. This dose is for children 1month-16yrs. Sheri correct me if he is wrong please… I would hate to give wrong information.

[Anonymous]

I haven’t personally seen dosing over 10mg/kg/day in infants before, but Zantac is an extremely safe medication so I wouldn’t expect any negative effects. Beth is right, the maximum total daily dosage for children 1 month to 16 years in the treatment of GERD is 300 mg, and in the treatment of ulcers is 150 mg. Either way, you are still below the maximum total daily dosage recommendations.

My only advice is that if you find you need this high of a dose for a prolonged period of time, it might be more beneficial to switch to a PPI. But in the short term, I don’t think there would be any problem.

[Author]

Posts