Home › Forums › Infant Reflux Support › HELP!!! › How much Prevacid compound?
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April 3, 2012 at 11:15 am #70177AnonymousInactive
Hi everyone, I’m new to this forum and after reading on here a lot is starting to make sense, for example her bottle of compounded prevacid seems to lose its effectiveness after a couple weeks, and I don’t think her Dr. is prescribing her enough to begin with. She is currently on Prevacid compound, the bottle says it’s 3MG/ML. She gets 2.5 ML twice a day and we’re careful about giving it on an empty stomach, eating 30 min later, and keeping her upright for 30 min after she’s done. She’s 3 months old tomorrow and 12.1 pounds. Is this enough Prevacid for her? It’s a battle getting her to eat, she still sounds all gurgly and congested, and she will eat about an ounce and then cry and arch, take a few more sips, do the same thing. It’s exhausting for both of us 🙁 I tried to look at the marci kids dosing chart but couldn’t figure it out.. is 2.5 ML twice a day enough for her? Thanks in advance, and I love this site I’m so glad I found it!!
April 3, 2012 at 8:06 pm #70181hellbenntKeymasteryou do not have to time the meds when it’s a compound. that’s why compounds can be a good thing. unfortunately, they are rarely made correctly.ack. you’re going to make me do math??
you better check it because I am making a disclaimer here- I can do zantac dosing w/ my eyes closed, but beyond that….First let’s get her weight in kilos:12.1 lbs = 5.5 kilosok, prevacid dosing for less than 3 months:1.5 to 1.75 mg/kg three times per dayI’ll calculate with 1.5 mg/kg5.5 x 1.5 = 8.25mgs a dose, and you give 3 doses of that dose, so it’s8.25 x 3 = 24.75mgs a day total for the day of prevacid…the bottle says it’s 3MG/ML. She gets 2.5 ML twice a day…this means that for every 1ml of liquid she gets 3mgs of the medicine prevacidso that’s 3mgs + 3mgs + 1.5mgs = 7.5mgs a dose7.5 + 7.5 = 15mgs a day currentlyshe could go up to 24.75 mgs a day, so you could add in one more dose of 2.5mls to get the dose to 22.5mgs a daythat’s still ‘under’ but it would be a good start…HOWEVER:I would TELL the pharmacist to PLEASE HUMOUR YOU and to make it this way:- Make sure that your pharmacist does not put any kind of flavoring agent in the compound.
- Make sure that the concentration is between 2 mg/mL and 4 mg/mL. This means that for every milliliter of suspension, you are giving between 2 and 4 milligrams of drug.
- Ask that your pharmacist make the compound with 16.8% sodium bicarbonate (if the total volume of each dose is less than 7 mL.) We also do not recommend that you give less than 3.5 mL of a PPI suspension at any concentration. This is because doses smaller than 3.5 mL do not provide enough buffer to adequately protect the drug from being destroyed by the acid that is present in the stomach.
It is important that the pharmacy does not add flavoring to the compound as it will almost certainly cause it to lose its stability much more quickly. It tastes pretty aweful this way, I know, but it’s better than the alternative.Ask for a printout of all the ingredients and amounts put into the compound. If you see any flavourings (simple syrup, sweet syrup, sweetener, bitter stop, stevia powder, oraplus, flavouring) then you know it’s not being made correctly. Then look for the amounts of bicarb and mg/ml as per the description in Natalia’s link[the information found in the previous/above posts]. I’ve yet to find a pharmacy who makes it correctly. It works for some, but never did for us.
If you do decide to go with the compound, I’d make sure to:
1. Have it made in 2 week doses only. They’ll say that prilosec is stable for a month if made unflavoured, but many people have found that it doesn’t work well after 2 weeks even if that’s true.
2. Get it made between 2-4mg/ml (yours is 5mg/ml) so that each dose is at least 3.5ml and made with 16.8 percent sodium bicarbonate.
3. Get them to prepare it without ANY flavourings whatsoever (including stevia powder, bitter stop, simple syrup, sweetener, ORA PLUS, or any other flavours including banana).
4. Shake the bottle EXTREMELY vigourously so that all the sediment that is on the bottom, which is the buffer, is mixed well into the solution. Sometimes it’s really hard to get it off the bottom, and it’s also hard to see, because they put it in a tan bottle so you can’t really see it there. But that’s the buffer, so if you don’t mix it then the med won’t work well.
5. REFRIGERATE!!!
6. Ask for a printout of all the ingredients put into the compound. We were told that Hailey’s suspension was unflavoured, only to find later on that they were adding all kinds of sweeteners to an otherwise unflavoured suspension that was rendering it ineffective.
April 4, 2012 at 6:16 pm #70199AnonymousInactiveTHANK YOU so much! That’s what I came up with too, adding one more dose. why on Earth would my pedi make such a big deal about timing it around a meal if I don’t have to???
April 4, 2012 at 6:20 pm #70200hellbenntKeymasterthey’re out of their minds! I’ve come to this conclusion after being on this board for EIGHT years, ha!
PLEASE make sure they make it correctly! TELL them. don’t ask!April 4, 2012 at 6:40 pm #70204AnonymousInactiveWow!! This literally just boggles my mind. Do the doctors just not realize how hard it is to time meds around meals for a reflux baby? Her eating is always so different, sometimes 2 oz and sometimes up to 6 oz, and I never know when to expect her to be hungry again because the formula she’s on is as thin as breastmilk and gets digested quickly (Nutramigen AA). I guess they just give patients the same instructions no matter what particular med it is. Wow.
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